Little Snitch has recently asked me if I'll allow "SLRuntimeLoader" to connect to go.Microsoft.com on port 80 (http). I don't have any Microsoft software installed and have no idea what this is. Unfortunately nothing useful comes up when doing a Google for it + "Mac" (or "OSX" either).
So far I've told Little Snitch to deny it just to be on the safe side and have had no adverse affect.